In Silico Investigations on Basal Stem Rot Disease and Biocontrol in Elaeis Guineensis
Ezebuo Fortunatus Chidolue,
Lukong Colin Banboye,
Okafor Irene Ngozi,
Onuoha Maxwell Chijioke
Issue:
Volume 3, Issue 5, October 2015
Pages:
74-80
Received:
31 July 2015
Accepted:
8 August 2015
Published:
8 September 2015
Abstract: Palm oil is the main vegetable oil produced in Nigeria and Elaeis guineensis's health is crucial in obtaining maximum production of oil. The genus Ganoderma belongs to the family of Ganodermataceae, which causes white rots of hardwoods in many woody plants like E. guineensis by decomposing their lignin with peroxidase and laccase. Introducing endophytic bacteria to the roots of E. guineensis could lead to suppression in the growth of Ganoderma specie. This study investigated microbial natural biocides capable of controlling basal stem rot disease in E. guineensis. Homology modeling of ganodermal manganese dependent peroxidase and laccase was achieved with ModWeb online tool. Secondary metabolites were manually curated and lignin was modeled as guaiacol. Virtual screening was achieved with AutoDockVina® on Linux platform. The result showed that eight (8) compounds had better binding affinities when compared with guaiacol. Catechin and flavanone are lead secondary metabolites with biocontrol potential against G. lucidium and binds to the same site that guaiacol binds on ganodermal manganese dependent peroxidase and laccase while flavanone binds to a different site on laccase. Stem rot disease in E. guineensis could be better controlled with natural biocides in endophytic bacteria such as catechin and flavanone.
Abstract: Palm oil is the main vegetable oil produced in Nigeria and Elaeis guineensis's health is crucial in obtaining maximum production of oil. The genus Ganoderma belongs to the family of Ganodermataceae, which causes white rots of hardwoods in many woody plants like E. guineensis by decomposing their lignin with peroxidase and laccase. Introducing endop...
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